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Selphyl® is based on the principle and platelets possess all the essential elements needed for tissue. The Selphyl® System is designed for the safe and rapid preparation of Platelet-rich Fibrin Matrix (PRFM) from a small sample of blood at the patient point of care. During a short office visit (30 minutes), a small amount of the patient's own blood is drawn into a supernatant plasma/platelet suspension. The platelets and plasma are then transferred in a closed system to a second vacuum tube containing a small amount of calcium chloride solution. There is virtually no risk of allergic reaction. The Selphyl® PRFM System is used to rapidly collect and isolate a patient's own PRFM for injection and contains no animal or synthetic products. There may be some temporary discomfort during the injections. Like all injection procedures, one can experience occasional redness and bruising immediately following the treatment that resolves quickly. The number of treatments needed depends on each individual patient, the desired outcome, and your doctor's treatment plan. At Chameleon Spa patients first, have microneedling done with the Rejuvapen. As a collagen builder, the science has found that PRP injected into the skin does work, but no studies prove that rubbing it onto the skin will work.